Moderate and Severe Dental Fluorosis in the Rural Population of Anantapur, India: Change in Their Biological Susceptibility?

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dc.contributor.authorTrina Mylena García Escobar
dc.contributor.authorIván Valdivia Gandur
dc.contributor.authorWilson Astudillo Rozas
dc.contributor.authorOscar Aceituno-Antezana
dc.contributor.authorBalasubbaiah Yamadala
dc.contributor.authorVicente Lozano de Luaces
dc.contributor.authorEduardo Chimenos Küstner
dc.contributor.authorMaría Cristina Manzanares Céspedes
dc.date.accessioned2025-06-23T16:16:58Z
dc.date.available2025-06-23T16:16:58Z
dc.date.issued2022
dc.description.abstractDental fluorosis affects the quality of life. A cross-sectional, observational study was conducted in a community affected by endemic fluorosis for several generations with a conserved biological and social environment. The study included patients from the rural population of Anantapur, India. The Dean index (DI) and the Thylstrup and Fejerskov Index (TFI) were used for fluorosis classification. Additionally, water samples were collected for fluoride analysis, taken from the patients’ living areas. The statistical association between the variables was analyzed. In total, 785 patients between 10 and 60 years old were included in the study (58.7% women and 41.3% men). Fluorosis signs were found in 94.6% of patients examined using the DI and 94.4% using the TFI. Moderate–severe dental fluorosis was observed in 62.8% by DI and 73.1% by TFI consuming untreated water with up to 2.9 ppm of fluoride. Furthermore, moderate–severe dental fluorosis was observed in 33.2% by DI and 39.9% by TFI consuming water with 1.5 ppm of fluoride. The high prevalence of moderate–severe dental fluorosis in patients consuming water with a low fluoride concentration suggests that other factors are involved. Biological susceptibility change could play an essential role in the severity of dental fluorosis in populations exposed for several generations, affecting its actual and future quality of life.
dc.description.sponsorshipMINEDUC-UA project, code ANT 1855 and the Research Assistant Program, Vicerrectoría de Investigación Innovación y Postgrado-Universidad de Antofagasta
dc.identifier.doi10.3390/ijerph191811293
dc.identifier.issn16617827
dc.identifier.urihttps://repositorioabierto.uantof.cl/handle/uantof/536
dc.language.isoen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceInternational Journal of Environmental Research and Public Health
dc.titleModerate and Severe Dental Fluorosis in the Rural Population of Anantapur, India: Change in Their Biological Susceptibility?
dc.typeArticle
oaire.citation.volume36
organization.identifier.rorUniversidad de Antofagasta
uantof.identificator.departmentDepartamento de Odontología
uantof.identificator.departmentDepartamento Biomédico
uantof.identificator.facultyFacultad de Ciencias de la Salud
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Departamento de Odontología
Departamento Biomédico
Magister en Ciencias Biomédicas