Long COVIDamongBrazilian Adults and Elders 12 Months after Hospital Discharge: A Population-Based Cohort Study

Vista sencilla de ítem
dc.contributor.authorMaria Aparecida Salci
dc.contributor.authorLígia Carreira
dc.contributor.authorNatan Nascimento Oliveira
dc.contributor.authorNatan David Pereira
dc.contributor.authorEduardo Rocha Covre
dc.contributor.authorGiovanna Brichi Pesce
dc.contributor.authorRosana Rosseto Oliveira
dc.contributor.authorCarla Franciele Höring
dc.contributor.authorWanessa Cristina Baccon
dc.contributor.authorJesús Puente Alcaraz
dc.contributor.authorGiovana Alves Santos
dc.contributor.authorLudmila Lopes Maciel Bolsoni
dc.contributor.authorAndrés Gutiérrez Carmona
dc.contributor.authorJoão Ricardo Nickenig Vissoci
dc.contributor.authorLuiz Augusto Facchini
dc.contributor.authorCarlos Laranjeira
dc.date.accessioned2026-03-09T18:51:05Z
dc.date.available2026-03-09T18:51:05Z
dc.date.issued2024
dc.description.abstractAbstract: The persistence of symptoms for more than three months following infection with severe acute respiratory syndrome coronavirus 2 is referred to as “Long COVID”. To gain a deeper understanding of the etiology and long-term progression of symptoms, this study aims to analyze the prevalence of Long COVID and its associated factors in a cohort of Brazilian adults and elders, twelve months after hospital discharge. An observational, prospective, and follow-up study was performed with a cohort of adults and older adults diagnosed with COVID-19 in 2020 in the State of Paraná, Brazil. Twelve months after hospital discharge, patients answered a phone questionnaire about the persistence of symptoms after three levels of exposure to COVID-19’s acute phase (ambulatory, medical ward, and intensive care unit). According to the characteristics of participants, the prevalence of Long COVID-19 was calculated, and logistic regression analyses were conducted. We analyzed data from 1822 participants (980 adults [≥18–<60 years] and 842 older people [≥60 years]) across three exposure levels. The overall Long COVID prevalence was 64.2%. Long COVID was observed in 646 adults (55%; of which 326 were women) and 523 older people (45%; of which 284 were women). Females had a higher prevalence of long-term symptoms (52%) compared with men. The most common post-COVID-19 conditions in the 12-month follow-up were neurological (49.8%), followed by musculoskeletal (35.1%) and persistent respiratory symptoms (26.5%). Male individuals were less likely to develop Long COVID (aOR = 0.50). Other determinants were also considered risky, such as the presence of comorbidities (aOR = 1.41). Being an adult and having been hospitalized was associated with the development of Long COVID. The risk of developing Long COVID was twice as high for ward patients (aOR = 2.53) and three times as high for ICU patients (aOR = 3.56) when compared to non-hospitalized patients. Presenting clinical manifestations of digestive (aOR = 1.56), endocrine (aOR = 2.14), cutaneous (aOR = 2.51), musculoskeletal (aOR = 2.76) and psychological systems (aOR = 1.66) made adults more likely to develop Long COVID. Long COVID was present in a large proportion of people affected by the SARS-CoV-2 infection. Presence of Long COVID symptoms displayed a dose–response relationship with the level of disease exposure, with a greater prevalence of symptoms associated with the severe form in the acute period.
dc.description.sponsorshipMinistério da Ciência, Tecnologia, Inovações e Comunicações (FNDCT/MCTIC), Ministério da Saúde (MS) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)—Processo n◦ 402,882/2020-2 FCT—Fundação para a Ciência e a Tecnologia, I.P. (UIDB/05704/2020 and UIDP/05704/2020) and by the Scientific Employment Stimulus—Institutional Call
dc.identifier.doi10.3390/healthcare12141443
dc.identifier.issn22279032
dc.identifier.urihttps://repositorioabierto.uantof.cl/handle/uantof/648
dc.language.isoen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceHealthcare (Switzerland)
dc.titleLong COVIDamongBrazilian Adults and Elders 12 Months after Hospital Discharge: A Population-Based Cohort Study
dc.typeArticle
oaire.citation.volume12
organization.identifier.rorUniversidad de Antofagasta
uantof.identificator.departmentDepartamento de Enfermería
Archivos
Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
healthcare-12-01443 (1).pdf
Tamaño:
688.17 KB
Formato:
Adobe Portable Document Format
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
1.71 KB
Formato:
Item-specific license agreed to upon submission
Descripción:
Descargar
Colecciones
Departamento Enfermeria