A Regenerative Endodontic Approach in Mature Ferret Teeth Using Rodent Preameloblast-conditioned Medium
| dc.contributor.author | Bucchi, Cristina | |
| dc.contributor.author | Gimeno-Sandig, Álvaro | |
| dc.contributor.author | Valdivia-Gandur, Ívan | |
| dc.contributor.author | Céspedes-Manzanares, Cristina | |
| dc.contributor.author | Maria de Anta, Josep | |
| dc.date.accessioned | 2026-01-12T12:58:26Z | |
| dc.date.available | 2026-01-12T12:58:26Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Background: This study evaluated the effectiveness of a regenerative endodontic approach to regenerate the pulp tissue in mature teeth of ferret. The presence of odontoblastlike cells in the newly-formed tissue of teeth treated with or without preameloblast-conditioned medium was evaluated based on morphological criteria. Materials and Methods: Twenty-four canines from six ferrets were treated. The pulp was removed, and the apical foramen was enlarged. After inducing the formation of a blood clot, a collagen sponge with or without preameloblast-conditioned medium was placed underneath the cementoenamel junction. The samples were analyzed at the eighth week of follow-up. Results: Vascularized connective tissue was observed in 50% of teeth, without differences between groups. The tissue occupied the apical third of the root canals. Odontoblast-like cells were not observed in any group. Conclusion: Revitalization of mature teeth is possible, at least in the apical third of the root canal. Further experimental research is needed to produce more reliable outcomes. | |
| dc.description.sponsorship | Faculty of Dentistry of the University of Barcelona MINEDU-CUA project code ANT 1755. | |
| dc.identifier.doi | 10.21873/invivo.11584 | |
| dc.identifier.issn | 0258-851X | |
| dc.identifier.uri | https://repositorioabierto.uantof.cl/handle/uantof/605 | |
| dc.language.iso | en | |
| dc.publisher | Instituto Internacional de Investigación Anticancerígena | |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | In Vivo | |
| dc.subject | Regenerative endodontics | |
| dc.subject | revitalization: mature teeth | |
| dc.subject | ferrets | |
| dc.subject | pulp regeneration | |
| dc.title | A Regenerative Endodontic Approach in Mature Ferret Teeth Using Rodent Preameloblast-conditioned Medium | |
| dc.type | Article | |
| oaire.citation.endPage | 1150 | |
| oaire.citation.issue | 4 | |
| oaire.citation.startPage | 1143 | |
| oaire.citation.volume | 33 | |
| organization.identifier.ror | https://ror.org/04eyc6d95 | |
| organization.legalName | Universidad de Antofagasta | |
| uantof.identificator.department | Departamento Biomédico | |
| uantof.identificator.department | Departamento de Odontología | |
| uantof.identificator.faculty | Facultad de Ciencias de la Salud | |
| uantof.identificator.faculty | Facultad de Medicina y Odontología |